When the FBI takes on a case of disappearing college girls, Jack Crawford recruits Will Graham, a gifted criminal profiler with a unique view into the psyche of serial killers, to consult. Jack also seeks the help of Dr. Hannibal Lecter, a brilliant psychiatrist
Will and Jack race to apprehend a serial killer using humans as fertilizer
Abigail Hobbs comes out of her coma with new information about her father
A series of family murders takes place
Jack and Will search for a killer who turns his victims into angels
The Chesapeake Ripper taunts Jack Crawford with guilt from the past
Will races to stop a rogue surgeon extracting organs from his victims
A deadly symphony hall killing forces Will to hunt a defiant killer
Will, Jack and the BAU team hunt for a serial killer who creates a totem pole out of his victims' bodies
Will tracks a killer with mental instability similar to his own
When Dr. Gideon escapes to terrorize Alana and Dr. Chilton, Hannibal and Will go on the hunt
Hannibal convinces Jack and Alana that Will could be the copycat killer
Hannibal frames Will, convincing Jack and Alana that Will's the copycat killer