Megumi hates living in the small village of Sotoba. She dreams of graduating from high school and moving to the city. Only two things hold her interest in the village, the giant European Mansion that was recently built atop a hillside and the boy Yuuki Natsuno

Megumi is dead and a burial is held for her. Doctor Ozaki is shocked at her sudden death and requests permission to perform an autopsy to determine the exact cause of her death but Megumi's father refuses. Later two more villagers die suddenly

Dr. Ozaki is convinced that Nao Yasumori has contracted the same illness that killed Megumi and several other in the village. He conducts numerous tests, all of which return conflicting results that do not match any known disease

Dr. Ozaki holds a meeting with the staff at the clinic and announces his belief that an epidemic of unknown origin is present in the town and his killed 19 people. He asks them to be vigilant in looking for people exhibiting the known symptoms but not to tell anyone in fear of starting a mass panic

Seishin talks to the relatives of the recently deceased and discovers the pattern that all of them became ill and weak only a few days before they died and that many quit their jobs before becoming ill. He also learns that many families have suddenly picked up moved in the middle of the night without telling anyone. Tooru dies suddenly, and at the funeral Natsuno and Masao get in an argument that ends with Masao running home crying complaining about how no one appreciates him

Natsuno investigates local stories of the "Risen" after seeing that someone had disturbed the torn-up pieces of Megumi's letter he threw out. Meanwhile, Masao's brother Hiromi has died of the same mysterious causes, and Masao is bedridden with peculiar bite wounds. Seishin meets with Dr

Masao awakens to find himself lying on a bed of flowers, six feet under. Natsuno joins forces with Kaori and Akira and convinces them to help him dig up Megumi’s grave to confirm if she is really dead or if she has “risen”. Meanwhile after his brief encounter with Natsuno, Dr

Natsuno, Kaori and Akira dig up Megumi’s grave to confirm if she has truly risen or not. Finding her coffin empty Kaori is suddenly attack by a strange man whose body is as cold as a corpse. Later unbeknownst to them Natsuno’s parents are visited by a strange girl who asks to be let into the house

Dr. Ozaki and Seishin vainly try to save an elderly patients life. After a blood transfusion seems to return her strength Dr

Natsuno house is visited by a strange young girl who demands to be invited in. When Natsuno returns home his parents tell him about the girl but she is gone. Realizing that his parents have given permission to the vampire to enter his house at any time he prepares for them to come for him

While Sotoba's villagers are debating the cause of the frequent deaths, the town shaman points her finger at the residents of Kanemasa mansion

Natsuno learns more about the Shiki and warns Kaori and Akira to leave town before it is to late

Natsuno may be dead but will he rise? Dr. Ozaki discovers that his wife is already in the final stages of having her blood drained. After she flat lines during the night he tells everyone that he will take care of her, but how does one take care of a dead person?

Kaori's father suddenly collapses. At the clinic, Dr. Ozaki studies his wife's corpse for clues on how to combat the Shiki

Dr. Ozaki tries to tell the townspeople the truth but is laughed off by the villagers believing that he is overworked at the clinic. He then tries to gather evidence to inform the outside world of what is occurring only to find that the Shiki have taken control of the local government and have altered all records so that no one has died in the town on paper

Kaori and Akira find their mother near death. Akira decides to take action and goes to the temple to collect talismans to ward off the Shiki while Kaori prepares stakes. At the same time Tooru is invited to tea with Sunako and learns of her origins as a Shiki

Seishin finds that his bed ridden father has disappeared without a trace. Kaori shows up at the temple covered in dirt her hair and eyes crazed with desperation and begs Seishin to give her last rights so that she will be ready when Megumi comes to kill her like the rest of her family. Dr

Natsuno is paid a visit by Tatsumi who informs him that he is one of only four known “werewolf” Shiki, those that can walk in the open sun. That night Tooru is taken to the huts where the Shiki have been putting bodies waiting to see if they turn, inside he finds nurse Ritsuko has turned but has politely refused to drink any blood. At the same time Dr

With the village finally believing Dr. Ozaki about the Shiki they begin to plan on how to exterminate them. Sunako hearing about Chizuro’s death orders Tatsumi to prepare the Shiki to finish off the village by killing or turning the bitten on the survivors

With the first day drawing to a close the village has killed many Shiki but Dr. Ozaki believes that they haven’t most of them. Tooru is forced to make a decision about Ritsuko refusing to drink blood and as dawn breaks on the 2nd day a new form off attack is revealed by the Shiki

The villagers finally discover where Sunako is hiding. Tatsumi creates a distraction to lure them away while Seishin tries to carry her to safety

The mountain is on fire and threatens to engulf the entire town. At the same time the final Shiki make their final effort to escape