Integra Hellsing takes command of a small Hellsing unit in Cheddar after reports of people in the village going missing by a seemingly normal priest reaches the authorities. After D11 teams were deployed to investigate with several deaths, Alucard is deployed. Seras Victoria, a female D11 operator, is fighting her ex-D11 colleagues that turned into zombies after getting into a previous fight with ghouls

Seras' new life in the Hellsing organization is a bit tough. Having been counted as 'lost' at the Cheddar incident, she now serves for a group dedicated to the eradication of vampires. Though she seems to have trouble adjusting, many are tolerant of her, and her new life, though the tolerance only goes so far

Something odd is happening - vampires seem to be growing in number. And when an Italian college student is found to have a computer chip, which has apparently made him into an 'artificial' vampire, it raises more than a few eyebrows. Even though the chip is removed, the student revives, killing many on his search for his lover, who he was caught in the act of making one of his own

The Hellsing Organization sets out to investigate a series of ""snuff films"" floating about the Internet, after footage of one of their own being killed begins to make the rounds. Meanwhile, Seras deploys with her unit, now under the command of a former SAS officer who seem to have a particularly distasteful attitude towards her, to silence an apartment building crawling with ghouls. As the raid unfolds, the secrecy surrounding the very existence of the Hellsing Organization is thrown in jeopardy when a mole broadcasts footage of the assault on live television

Seras is still having a hard time dealing with the fact that she's a vampire, but is slowly adapting. However, the real bad news is the violent and crazy Valentine Brothers who decide to take out the Hellsing crew once and for all by means of infiltrating their headquarters with their Ghoul Army

Picking up where Brotherhood left off. Luke and Jan, the Valentine Brothers, lay siege to the headquarters of the Hellsing organization, the Royal Order of Religious Knights. After numerous humans have been killed and eaten by an army of ghouls, Victoria, Walter, and Arucard finally get around to striking back

More than half of the members of the Royal Order of Religious Knights were massacred due to the last attack on them that was conducted by the Valentine Brothers. Sir Integra Hellsing, Arucard, and Seras must now hunt down the perpetrators. The suspects include the Vatican's Iscariot Organization

Victoria learns more about whoever is making the "artificial vampirization catalyst semiconductor" or "freak chips" that turn humans into second-class ghouls

Alucard meets a new enemy. that could be more powerful than he. An original undead, Incognito

Almost commiting suicide, Integra is being operated on to save her life. While the operation is going on, we see the history of Integra's ascension to power. We learn that her uncle tried to take her father's place as head of the Hellsing organization, and in attempt to assume power, tried to kill off Integra while Walter was away (presumably on duty)

With the freak problems getting much worse, the Royal Knights arrange a meeting at Westminster with Integra to discuss the matter. In addition, the Queen will be meeting with them so they can conduct a ceremony with Integra. Because of the danger that the freaks may pose, the media is told that the meeting will take place at the Tower of London while in truth Integra's ritual is at the Hellsing castle

All out war breaks out at the Tower of London and Integra's meeting with her majesty is cancelled. The remaining Hellsing members are at the decoy spot of the meeting, battling ghouls of the S.A

This episode opens with the fierce battle between Incognito and Lord Alucard. Eventually, as the battle ensues, Incognito manages to "destroy" Alucard with his own "bullets that store the power of the human God". Near the beginning of this battle Ceras Victoria became injured and realizes she must drink blood to heal herself, she discovers her first taste of true blood from her fallen master